Human Aldose reductase Like Protein 2,ARL2 ELISA KIT

SKU: E4160hu

Size:96 Tests-1 Kit

Background:Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle. {ECO:0000269|PubMed:10831612, ECO:0000269|PubMed:16525022, ECO:0000269|PubMed:18234692, ECO:0000269|PubMed:18588884, ECO:0000269|PubMed:20740604}.

Research_area:

Applications:ELISA

Target_protein:ARL2

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.39ng/ml

Detection range:0.75-48ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Aldose reductase Like Protein 2

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P36404

MASS(Da):20878

GeneID:402

Synonyms:ARL2

Gene names:ARL2

Standard solution:96ng/ml