Human Agouti Related Protein, AGRP ELISA Kit

SKU: E1478Hu

Size:96 Tests-1 Kit

Background:Plays a role in weight homeostasis. Involved in the control of feeding behavior through the central melanocortin system. Acts as alpha melanocyte-stimulating hormone antagonist by inhibiting cAMP production mediated by stimulation of melanocortin receptors within the hypothalamus and adrenal gland. Has very low activity with MC5R (By similarity). Is an inverse agonist for MC3R and MC4R being able to suppress their constitutive activity. It promotes MC3R and MC4R endocytosis in an arrestin-dependent manner.

Research_area:Signal Transduction; Neuroscience; Cardiovascular; Metabolism

Applications:ELISA

Target_protein:AGRP

Reactivity:Human

Assay type:Sandwich

Sensitivity:10.03ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Agouti Related Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O00253

MASS(Da):14,440

GeneID:181

Synonyms:Agouti-related protein;AGRP;AGRT;ART;ASIP2

Gene names:AGRP

Standard solution:4800ng/L