Human Adp-Ribosylation Factor 6, ARF6 ELISA Kit

SKU: E4599Hu

Size:96 Tests-1 Kit

Background:GTP-binding protein involved in protein trafficking that regulates endocytic recycling and cytoskeleton remodeling (PubMed: 11266366, PubMed: 21170023, PubMed: 16737952, PubMed: 7589240, PubMed: 18400762). Required for normal completion of mitotic cytokinesis (By similarity). Plays a role in the reorganization of the actin cytoskeleton and the formation of stress fibers (By similarity). Involved in the regulation of dendritic spine development, contributing to the regulation of dendritic branching and filopodia extension (PubMed: 14978216). Plays an important role in membrane trafficking, during junctional remodeling and epithelial polarization. Regulates surface levels of adherens junction proteins such as CDH1 (By similarity). Required for NTRK1 sorting to the recycling pathway from early endosomes (By similarity). (Microbial infection) Functions as an allosteric activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase.

Research_area:Signal Transduction

Applications:ELISA

Target_protein:ARF6

Reactivity:Human

Assay type:Sandwich

Sensitivity:1.59ng/L

Detection range:3-900ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Adp-Ribosylation Factor 6

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P62330

MASS(Da):20,082

GeneID:382

Synonyms:ADP-ribosylation factor 6;ARF 6;ARF6

Gene names:ARF6

Standard solution:960ng/L