Human Adenylate cyclase type 8,ADCY8 ELISA KIT

SKU: E2033Hu

Size:96 Tests-1 Kit

Background:Catalyzes the formation of cAMP in response to calcium entry leadings to cAMP signaling activation that affect processes suche as synaptic plasticity and insulin secretion. Plays a role in many brain functions, such as learning, memory, drug addiction, and anxiety modulation through regulation of synaptic plasticity by modulating long-term memory and long-term potentiation (LTP) through CREB transcription factor activity modulation. Plays a central role in insulin secretion by controlling glucose homeostasis through glucagon-like peptide 1 and glucose signaling pathway and maintains insulin secretion through calcium-dependent PKA activation leading to vesicle pool replenishment. Also, allows PTGER3 to induce potentiation of PTGER4-mediated PLA2 secretion by switching from a negative to a positive regulation, during the IL1B induced-dedifferentiation of smooth muscle cells. {ECO:0000250|UniProtKB:P40146}.

Research_area:

Applications:ELISA

Target_protein:ADCY8

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.07ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Adenylate Cyclase 8, Brain

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P40145

MASS(Da):140122

GeneID:114

Synonyms:ADCY8

Gene names:ADCY8

Standard solution:24ng/ml