Human Activin A ELISA Kit PicoKine®

SKU: EK0301

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Human

Applications: ELISA

Application Details:

Gene Name: INHBA

Specificity: Natural and recombinant human Activin A

Background: Activin A is a homodimer of 14kDa beta-A. Activin A, a cytokine member of the transforming growth factor-beta superfamily, is expressed locally by the mesenchymal component of the hemopoietic microenvironment. Its expression is regulated on the mRNA level by different cytokines, and the biological activity of the protein is tightly controlled by several inhibitory molecules. Inhibins and activins are members of the transforming growth factor beta superfamily and are known to modulate the growth and differentiation of several cell types. Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins. The standard product used in this kit is recombinant Activin A, which is composed of two single chains of 116 amino acids with the molecular mass of 26KDa.

Immunogen: Expression system for standard: CHO; Immunogen sequence: G311-S426

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Reference:

Uniprot ID: A4D1W7

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 3624

Protein Name: Inhibin beta A chain

Gene Full Name: inhibin subunit beta A

Synonyms: Activin beta A chain; EDF; FRP; INHBA; Inhibin Beta A; Inhibin beta A chain; Inhibin β-A; inhibin; beta A