Human Abnormal Spindle-like Microcephaly-associated Protein, ASPM ELISA Kit

SKU: E4890Hu

Size:96 Tests-1 Kit

Background:Involved in mitotic spindle regulation and coordination of mitotic processes. The function in regulating microtubule dynamics at spindle poles including spindle orientation, astral microtubule density and poleward microtubule flux seems to depend on the association with the katanin complex formed by KATNA1 and KATNB1. Enhances the microtubule lattice severing activity of KATNA1 by recruiting the katanin complex to microtubules. Can block microtubule minus-end growth and reversely this function can be enhanced by the katanin complex (PubMed: 28436967). May have a preferential role in regulating neurogenesis.

Research_area:Others

Applications:ELISA

Target_protein:ASPM

Reactivity:Human

Assay type:Sandwich

Sensitivity:7.35ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Abnormal Spindle-Like Microcephaly-Associated Protein

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q8IZT6

MASS(Da):409,800

GeneID:259266

Synonyms:Abnormal spindle protein homolog;Abnormal spindle-like microcephaly-associated protein;Asp homolog;ASPM

Gene names:ASPM

Standard solution:3200ng/L