Human Α1-Antitrypsin, A1-AT ELISA Kit

SKU: E0753Hu

Size:96 Tests-1 Kit

Background:Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. [Short Peptide from AAT]: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).

Research_area:Cardiovascular

Applications:ELISA

Target_protein:SERPINA1

Reactivity:Human

Assay type:Sandwich

Sensitivity:0.024mg/ml

Detection range:0.05-15mg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:alpha1-Antitrypsin

Species:Human

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P01009

MASS(Da):46,737

GeneID:5265

Synonyms:Alpha-1 protease inhibitor;Alpha-1-antiproteinase;Alpha-1-antitrypsin;Serpin A1;SERPINA 1;SERPINA1;Short Peptide from AAT;SPAAT

Gene names:SERPINA1

Standard solution:19.2mg/ml