HSP90 antibody , Cat. # FNab04052

SKU: FNab04052

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:4G10

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:HSP90, encoded by HSP90AA1, is a constitutively and ubiquitously expressed molecular chaperone that is crucial for the stability and function of many proteins. HSP90 provides chaperoning activity for client proteins; many of them are members of oncogenic pathways, indicating its implication in tumor malignancy. HSP90 mainly resides in the cytosol, while it can also be released to the extracellular space. Secreted Hsp90 is a C-terminal truncated form. It has been reported that the level of plasma Hsp90 is positively correlated with tumor malignancy in clinical cancer patients, and can be a promising diagnostic marker for tumor malignancy in clinical application.

Immunogen:heat shock protein 90kDa alpha(cytosolic), class A member 1

Synonyms:HSP 86, HSP86, Hsp89, HSP89A, HSP90, HSP90A, HSP90AA1, HSP90N, HSPC1, HSPCA, HSPCAL1, HSPCAL4, HSPN, LAP2

Observed MW:90 kDa

Uniprot ID:P07900

Reactivity:Human, Mouse, Rat

Tested Application:ELISA, WB, IHC, FC

Recommended dilution:WB: 1:1000-1:8000; IHC: 1:50-1:500

Gene ID:3320

Research Area:Neuroscience, Cardiovascular, Metabolism, Signal Transduction