HSD17B10 Antibody - Cat. #: CSB-PA909726

SKU: CSB-PA909726

Size :100ul

Clone Number:

Aliases:17 beta hydroxysteroid dehydrogenase 10 antibody; 17 beta hydroxysteroid dehydrogenase type 10 antibody; 17-beta-HSD 10 antibody; 17-beta-hydroxysteroid dehydrogenase 10 antibody; 17b HSD10 antibody; 3 hydroxy 2 methylbutyryl CoA dehydrogenase antibody; 3 hydroxyacyl CoA dehydrogenase type 2 antibody; 3 hydroxyacyl CoA dehydrogenase type II antibody; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase antibody; 3-hydroxyacyl-CoA dehydrogenase type II antibody; 3-hydroxyacyl-CoA dehydrogenase type-2 antibody; AB binding alcohol dehydrogenase antibody; ABAD antibody; Ads9 antibody; Amyloid beta binding polypeptide antibody; Amyloid beta peptide binding alcohol dehydrogenase antibody; Amyloid beta peptide binding protein antibody; Amyloid beta peptide binding protein antibody; CAMR antibody; DUPXp11.22 antibody; Endoplasmic Reticulum Amyloid Binding Protein antibody; Endoplasmic reticulum associated amyloid beta peptide binding protein antibody; Endoplasmic reticulum-associated amyloid beta-peptide-binding protein antibody; ER associated amyloid beta-binding protein antibody; ERAB antibody; HADH 2 antibody; HADH2 antibody; HCD 2 antibody; HCD2 antibody; HCD2_HUMAN antibody; Hsd17b10 antibody; Hydroxyacyl CoA Dehydrogenase type II antibody; Hydroxyacyl Coenzyme A dehydrogenase type II antibody; Hydroxysteroid (17 beta) dehydrogenase 10 antibody; Mental retardation X linked syndromic 11 antibody; MHBD antibody; Mitochondrial L3 Hydroxyacyl CoA Dehydrogenase antibody; Mitochondrial ribonuclease P protein 2 antibody; Mitochondrial RNase P protein 2 antibody; MRPP2 antibody; MRX17 antibody; SCHAD antibody; SDR5C1 antibody; Short chain dehydrogenase/reductase family 5C member 1 antibody; Short chain L 3 hydroxyacyl CoA dehydrogenase type 2 antibody; Short chain type dehydrogenase/reductase XH98G2 antibody; Short-chain type dehydrogenase/reductase XH98G2 antibody; Type 10 17b HSD antibody; Type 10 17beta hydroxysteroid dehydrogenase antibody; Type II HADH antibody; XH98G2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q99714

Immunogen:Synthesized peptide derived from Human ERAB.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Functions in mitochondrial tRNA maturation. Part of mitochondrial ribonuclease P, an enzyme composed of MRPP1/TRMT10C, MRPP2/HSD17B10 and MRPP3/KIAA0391, which cleaves tRNA molecules in their 5'-ends. Catalyzes the beta-oxidation at position 17 of androgens and estrogens and has 3-alpha-hydroxysteroid dehydrogenase activity with androsterone. Catalyzes the third step in the beta-oxidation of fatty acids. Carries out oxidative conversions of 7-alpha-OH and 7-beta-OH bile acids. Also exhibits 20-beta-OH and 21-OH dehydrogenase activities with C21 steroids. By interacting with intracellular amyloid-beta, it may contribute to the neuronal dysfunction associated with Alzheimer disease (AD).

Shi Du Yan, J. Biol. Chem., Jan 1999; 274: 2145.
C Hansis, Eur. J. Biochem., Nov 1998; 258: 53.
Xue-Ying He, Eur. J. Biochem., Sep 2001; 268: 4899.
Natalie A. Sims, J. Clin. Invest., May 2003; 111: 1319.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:HSD17B10

Research Areas:Neuroscience;Tags & Cell Markers;Metabolism