HMG-I/HMG-Y Rabbit pAb

SKU: ES15695

Size: 100μL

Source:Rabbit

Applications:WB;IHC;IF;ELISA

Reactivity:Human; Mouse; Rat

Dilution:Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

Immunogen:Synthesized peptide derived from human HMG-I/HMG-Y . AA20-60

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:3159

Human_swiss_prot_no:P17096

Subcellular_location:Nucleus. Chromosome.

Other_name:High mobility group protein HMG-I/HMG-Y (HMG-I(Y);High mobility group AT-hook protein 1;High mobility group protein A1;High mobility group protein R)

Background:This gene encodes a chromatin-associated protein involved in the regulation of gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of AT-rich regions in double-stranded DNA. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been identified on multiple chromosomes. [provided by RefSeq, Jan 2016],