Histone H2B (Acetyl Lys117) Rabbit Polyclonal Antibody

SKU: BT-AP10417

Size:100μL

Background:Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A| H2B| H3| and H4). The chromatin fiber is further compacted through the interaction of a linker histone| H1| with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a testis/sperm-specific member of the histone H2B family. Transcripts from this gene contain a palindromic termination element.

Research_area:Epigenetics and nuclear signaling

Target_protein:HIST1H2BA

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone H2B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):13970

UniProt accession:Human: Q96A08; Mouse: P70696; Rat: Q00729

Synonyms:Histone H2B ;Acetyl Lys117; Histone H2B type 1-A; Histone H2B; testis; Testis-specific histone H2B

GeneID:Human: 255626; Mouse: 319177; Rat: 24829