Histone H1 (Acetyl Lys66/63/64) Rabbit Polyclonal Antibody

SKU: BT-AP02978

Size:100μL

Background:Histones are basic nuclear proteins responsible for nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A| H2B| H3| and H4) form an octamer| around which approximately 146 bp of DNA is wrapped in repeating units| called nucleosomes. The linker histone| H1| interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.

Research_area:Epigenetics and nuclear signaling

Target_protein:HIST1H1A

applications:WB, ELISA

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Histone H1

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):23650

UniProt accession:Human: Q02539/P16403/P16402/P10412; Mouse: P43275; Rat: D4A3K5

Synonyms:Histone H1 ;Acetyl Lys66/63/64; Histone H1.1; Histone H1a

GeneID:Human: 3024; Mouse: 80838; Rat: 291145