HDAC4 Monoclonal Antibody

SKU: BT-MCA2920

Size:100μL

Background:Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:HDAC4

applications:WB

Reactivity:Human

Clonality:Monoclonal

Clone ID:7B2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:HDAC4

Immunogen:Purified recombinant fragment of human HDAC4 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS containing 0.05% sodium azide.

Concentration:

Molecular weight(Da):119kDa

UniProt accession:P56524

Synonyms:HD4, HDACA, HA6116, HDAC-A, KIAA0288, HDAC4

GeneID:9759