HDAC1 Monoclonal Antibody

SKU: BT-MCA3625

Size:100μL

Background:Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis.

Research_area:Epigenetics and Nuclear Signaling

Target_protein:HDAC1

applications:WB, IHC, ICC, FCM

Reactivity:

Clonality:Monoclonal

Clone ID:2A1D3

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:HDAC1

Immunogen:Purified recombinant fragment of human HDAC1 (AA: 321-482) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):55.1kDa

UniProt accession:Q13547

Synonyms:HD1, RPD3, KDAC1, GON-10, RPD3L1

GeneID:3065