Guinea Pig Interleukin-12 subunit beta,IL12B ELISA KIT

SKU: E0130Gp

Size:96 Tests-1 Kit

Background:Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC. {ECO:0000250}.; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis (By similarity). {ECO:0000250}.

Research_area:

Applications:ELISA

Target_protein:IL12B

Reactivity:Guinea Pig

Assay type:Sandwich

Sensitivity:7.48ng/L

Detection range:15-3000ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:Interleukin-12 subunit beta

Species:Guinea Pig

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q924V5

MASS(Da):37632

GeneID:100135554

Synonyms:IL12B

Gene names:IL12B

Standard solution:3200ng/L