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GeneBio Systems

GTF2A2 Polyclonal Antibody

GTF2A2 Polyclonal Antibody

E-AB-18882

£423.00 GBP
£423.00 GBP
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Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: GTF2A2

Target Synonym: General transcription factor IIA;General transcription factor IIA subunit 2;General transcription factor IIA; 2 (12kD subunit);General transcription factor IIA; 2; 12kDa;gtf2a2;HsT18745;T2AG;TF2A2;TFIIA 12;TFIIA;TFIIA gamma ;TFIIA p12 subunit;TFIIA-12;TFIIA-gamma;TFIIA12;TFIIAS;Transcription initiation factor IIA gamma chain;Transcription initiation factor IIA subunit 2

Research Areas: Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Mouse;Rat

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P52657

Accession:

Background: Accurate transcription initiation on TATA-containing class II genes involves the ordered assembly of RNA polymerase II (POLR2A; MIM 180660) and the general initiation factors TFIIA, TFIIB (MIM 189963), TFIID (MIM 313650), TFIIE (MIM 189962), TFIIF (MIM 189968), TFIIG/TFIIJ, and TFIIH (MIM 189972). The first step involves recognition of the TATA element by the TATA-binding subunit (TBP; MIM 600075) and may be regulated by TFIIA, a factor that interacts with both TBP and a TBP-associated factor (TAF; MIM 600475) in TFIID. TFIIA has 2 subunits (43 and 12 kD) in yeast and 3 subunits in higher eukaryotes. In HeLa extracts, it consists of a 35-kD alpha subunit and a 19-kD beta subunit encoded by the N- and C-terminal regions of GTF2A1 (MIM 600520), respectively, and a 12-kD gamma subunit encoded by GTF2A2 (DeJong et al., 1995 [PubMed 7724559]).

Concentration: 0.54 mg/mL

Immunogen: Fusion protein of human GTF2A2

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:30-1:150

Calculated MW:

ObservedMW:

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