GSTM5 Rabbit Polyclonal Antibody

SKU: BT-AP10307

Size:100μL

Background:Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present| eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha| kappa| mu| omega| pi| sigma| theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds| including carcinogens| therapeutic drugs| environmental toxins and products of oxidative stress| by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains| as well as in tissue expression patterns| to accommodate an increasing number of foreign compounds.

Research_area:Metabolism; Signal transduction

Target_protein:GSTM5

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:GSTM5

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):23980

UniProt accession:Human: P46439; Mouse: P48774; Rat: Q9Z1B2

Synonyms:GSTM5

GeneID:Human: 2949; Mouse: 14866; Rat: 100912430