GRIN2B Antibody - Cat. #: CSB-PA615671DSR2HU

SKU: CSB-PA615671DSR2HU

Size :50ul

Clone Number:

Aliases:AW490526 antibody; EIEE27 antibody; Glutamate [NMDA] receptor subunit epsilon 2 antibody; Glutamate [NMDA] receptor subunit epsilon-2 antibody; Glutamate Receptor Ionotropic N Methyl D Aspartate 2B antibody; Glutamate Receptor Ionotropic N Methyl D Aspartate subunit 2B antibody; Glutamate receptor ionotropic NMDA2B antibody; Glutamate receptor subunit epsilon 2 antibody; Glutamate receptor, ionotropic, NMDA2B (epsilon 2) antibody; GRIN 2B antibody; GRIN2B antibody; hNR 3 antibody; hNR3 antibody; MGC142178 antibody; MGC142180 antibody; MRD6 antibody; N methyl D asparate receptor channel subunit epsilon 2 antibody; N methyl D aspartate receptor subtype 2B antibody; N methyl D aspartate receptor subunit 2B antibody; N methyl D aspartate receptor subunit 3 antibody; N-methyl D-aspartate receptor subtype 2B antibody; N-methyl-D-aspartate receptor subunit 3 antibody; NMDA NR2B antibody; NMDA R2B antibody; NMDAR2B antibody; NMDE2 antibody; NMDE2_HUMAN antibody; NME2 antibody; NR2B antibody; NR3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q13224

Immunogen:Recombinant Human Glutamate receptor ionotropic, NMDA 2B protein (1185-1484AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:NMDA receptor subtype of glutamate-gated ion channels with high calcium permeability and voltage-dependent sensitivity to magnesium. Mediated by glycine. In concert with DAPK1 at extrasynaptic sites, acts as a central mediator for stroke damage. Its phosphorylation at Ser-1303 by DAPK1 enhances synaptic NMDA receptor channel activity inducing injurious Ca2+ influx through them, resulting in an irreversible neuronal death (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRIN2B

Research Areas:Neuroscience