GRHL1 Antibody - Cat. #: CSB-PA868368LA01HU

SKU: CSB-PA868368LA01HU

Size :50ul

Clone Number:

Aliases:Grainyhead-like protein 1 homolog antibody; grhl1 antibody; GRHL1_HUMAN antibody; LBP32 antibody; Mammalian grainyhead antibody; MGR antibody; NH32 antibody; TFCP2L2 antibody; Transcription factor CP2-like 2 antibody; Transcription factor LBP-32 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NZI5

Immunogen:Recombinant Human Grainyhead-like protein 1 homologprotein (1-95AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; Recommended dilution: WB:1:500-1:5000, IHC:1:200-1:500

Background:Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5\'-AACCGGTT-3\' (PubMed:12175488, PubMed:18288204). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier. There is no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity). Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed (PubMed:12175488).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Non-conjugated

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GRHL1

Research Areas:Epigenetics and Nuclear Signaling