GPR161 Antibody, HRP conjugated - Cat. #: CSB-PA04114B0Rb

SKU: CSB-PA04114B0Rb

Size :50ug

Clone Number:

Aliases:GPR161 antibody; G-protein coupled receptor 161 antibody; G-protein coupled receptor RE2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N6U8

Immunogen:Recombinant Human G-protein coupled receptor 161 protein (1-28AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalized into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:HRP

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GPR161

Research Areas:Others