GPC3 Monoclonal Antibody

SKU: BT-MCA3128

Size:100μL

Background:Cell surface heparan sulfate proteoglycans are composed of a membrane-associated protein core substituted with a variable number of heparan sulfate chains. Members of the glypican-related integral membrane proteoglycan family (GRIPS) contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol linkage. These proteins may play a role in the control of cell division and growth regulation. The protein encoded by this gene can bind to and inhibit the dipeptidyl peptidase activity of CD26, and it can induce apoptosis in certain cell types. Deletion mutations in this gene are associated with Simpson-Golabi-Behmel syndrome, also known as Simpson dysmorphia syndrome. Alternative splicing results in multiple transcript variants.

Research_area:Stem Cells

Target_protein:GPC3

applications:WB, IHC, ICC, FCM

Reactivity:Human, Mouse, Rat

Clonality:Monoclonal

Clone ID:9C2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:GPC3

Immunogen:Purified recombinant fragment of human GPC3 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Purified antibody in PBS with 0.05% sodium azide

Concentration:

Molecular weight(Da):65.5kDa

UniProt accession:P51654

Synonyms:SGB, DGSX, MXR7, SDYS, SGBS, OCI-5, SGBS1, GTR2-2

GeneID:2719