GP-39 rabbit pAb

SKU: ES15931

Size: 100μL

Source:Rabbit

Applications:IHC;IF;WB

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-200, WB 1:500-2000

Immunogen:Synthesized peptide derived from human GP-39

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):42kD

Human_gene_id:1116

Human_swiss_prot_no:P36222

Subcellular_location:Secreted, extracellular space . Cytoplasm . Cytoplasm, perinuclear region . Endoplasmic reticulum .

Other_name:Chitinase-3-like protein 1 (39 kDa synovial protein;Cartilage glycoprotein 39;CGP-39;GP-39;hCGP-39;YKL-40)

Background:Chitinases catalyze the hydrolysis of chitin, which is an abundant glycopolymer found in insect exoskeletons and fungal cell walls. The glycoside hydrolase 18 family of chitinases includes eight human family members. This gene encodes a glycoprotein member of the glycosyl hydrolase 18 family. The protein lacks chitinase activity and is secreted by activated macrophages, chondrocytes, neutrophils and synovial cells. The protein is thought to play a role in the process of inflammation and tissue remodeling. [provided by RefSeq, Sep 2009],