GLYCTK Antibody - Cat. #: CSB-PA219793

SKU: CSB-PA219793

Size :100ul

Clone Number:

Aliases:CG9886 like antibody; GLCTK_HUMAN antibody; Glycerate kinase antibody; Glyctk antibody; GLYCTK1 antibody; HBeAg binding protein 2 antibody; HBeAg binding protein 4 antibody; HBeAg-binding protein 4 antibody; HBeAgBP4A antibody; HBEBP2 antibody; HBEBP4 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8IVS8

Immunogen:Synthesized peptide derived from internal of Human GLCTK.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC, IF; WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500

Background:Defects in GLYCTK are the cause of D-glyceric aciduria (D-GA). D-GA is a rare metabolic disease characterized by chronic metabolic acidosis and a highly variable clinical phenotype. Clinical features range from an encephalopathic presentation with seizures, microcephaly, severe mental retardation and early death, to milder manifestations with only speech delay or even normal development. Belongs to the glycerate kinase type-2 family. 7 isoforms of the human protein are produced by alternative splicing.

Guo J.-H., DNA Seq. 17:1-7(2006).
Wan D., Proc. Natl. Acad. Sci. U.S.A. 101:15724-15729(2004).
Ota T., Nat. Genet. 36:40-45(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GLYCTK

Research Areas:Cancer;Metabolism;Signal transduction