GCAT Polyclonal Antibody

SKU: E-AB-52743

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:GCAT

Target Synonym:2 amino 3 ketobutyrate CoA ligase ;2 amino 3 ketobutyrate coenzyme A ligase; mitochondrial;2-amino-3-ketobutyrate coenzyme A ligase;AKB ligase;Aminoacetone synthase;GCAT;Glycine acetyltransferase;glycine C acetyltransferase ;glycine C acetyltransferase (2 amino 3 ketobutyrate coenzyme A ligase);KBL;KLB;mitochondrial

Research Areas:Cancer;Metabolism;Signal transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:O75600

Accession:

Background:The degradation of L-threonine to glycine consists of a two-step biochemical pathway involving the enzymes L-threonine dehydrogenase and 2-amino-3-ketobutyrate coenzyme A ligase. L-Threonine is first converted into 2-amino-3-ketobutyrate by L-threonine dehydrogenase. This gene encodes the second enzyme in this pathway, which then catalyzes the reaction between 2-amino-3-ketobutyrate and coenzyme A to form glycine and acetyl-CoA. The encoded enzyme is considered a class II pyridoxal-phosphate-dependent aminotransferase. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 14.

Concentration:1.08 mg/mL

Immunogen:Fusion protein of human GCAT

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:IHC 1:40-1:200

Calculated MW:

ObservedMW: