Galectin-3 Mouse mAb

SKU: EM1237

Size: 100μL

Source:Mouse

Applications:WB, IHC, ELISA

Reactivity:Human, Mouse

Dilution:WB 1:1,000-2,000 IHC 1:100-200 ELISA 10,000-50,000

Immunogen:Protein

Storage_stability:PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid repeated freeze-thaw cycles.

Clonality:Monoclonal

Isotype:IgG1

Concentration:1mg/mL

Observed_band(KD):26kDa

Human_gene_id:3958

Human_swiss_prot_no:P17931

Subcellular_location:Cytoplasm, Nucleus, Secreted, Spliceosome

Other_name:35 kDa lectin, CBP 35, CBP35, Gal 3, GAL3, Galactose specific lectin 3, Galactoside binding protein, GALBP, Galectin 3, Galectin-3, GALIG, IgE binding protein, L 31, Laminin binding protein, Lectin L 29, LGALS2, LGALS3, Mac 2 antigen, MAC2

Background:Galectin 3 is one of the more extensively studied members of this family and is a 30 kDa protein. Due to a C-terminal carbohydrate binding site, Galectin 3 is capable of binding IgE and mammalian cell surfaces only when homodimerized or homooligomerized. Galectin 3 is normally distributed in epithelia of many organs, in various inflammatory cells, including macrophages, as well as dendritic cells and Kupffer cells. The expression of this lectin is up-regulated during inflammation, cell proliferation, cell differentiation and through trans-activation by viral proteins.