GAB2 Antibody - Cat. #: CSB-PA923404

SKU: CSB-PA923404

Size :50ul

Clone Number:

Aliases:GAB 2 antibody; Gab2 antibody; GAB2_HUMAN antibody; Grb 2 associated binder 2 antibody; GRB 2 associated binding protein 2 antibody; Grb2 associated binder 2 antibody; GRB2 associated binder 2 pp100 antibody; GRB2 associated binding protein 2 antibody; GRB2-associated binder 2 antibody; GRB2-associated-binding protein 2 antibody; Growth factor receptor bound protein 2 associated protein 2 antibody; Growth factor receptor bound protein 2-associated protein 2 antibody; KIAA0571 antibody; p97 antibody; PH domain containing adaptor molecule p97 antibody; pp100 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9UQC2

Immunogen:Fusion protein of Human GAB2

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:5000, WB:1:500-1:2000, IHC:1:50-1:200

Background:This gene is a member of the GRB2-associated binding protein (GAB) gene family. These proteins contain pleckstrin homology (PH) domain, and bind SHP2 tyrosine phosphatase and GRB2 adapter protein. They act as adapters for transmitting various signals in response to stimuli through cytokine and growth factor receptors, and T- and B-cell antigen receptors. The protein encoded by this gene is the principal activator of phosphatidylinositol-3 kinase in response to activation of the high affinity IgE receptor. Two alternatively spliced transcripts encoding different isoforms have been described for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:GAB2

Research Areas:Neuroscience?Cancer;Signal transduction