FZD6 Antibody - Cat. #: CSB-PA032335

SKU: CSB-PA032335

Size :50ul

Clone Number:

Aliases:Frizzled 6 seven transmembrane spanning receptor antibody; Frizzled drosophila homolog of 6 antibody; Frizzled family receptor 6 antibody; Frizzled homolog 6 (Drosophila) antibody; Frizzled homolog 6 antibody; Frizzled-6 antibody; Frizzled6 antibody; Fz 6 antibody; Fz-6 antibody; Fz6 antibody; FZD 6 antibody; Fzd6 antibody; FZD6_HUMAN antibody; Hfz 6 antibody; hFz6 antibody; NDNC10 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O60353

Immunogen:Synthetic peptide of Human FZD6

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, IHC; ELISA:1:2000-1:10000, IHC:1:100-1:300

Background:This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FZD6

Research Areas:Others