FXL18 Rabbit Polyclonal Antibody

SKU: BT-AP02756

Size:100μL

Background:The protein encoded by this gene is a member of a family of proteins that contain an approximately 40-amino acid F-box motif. This motif is important for interaction with SKP1 and for targeting some proteins for degradation. The encoded protein has been shown to control the cellular level of FBXL7| a protein that induces mitotic arrest| by targeting it for polyubiquitylation and proteasomal degradation. Members of the F-box protein family| such as FBXL18| are characterized by an approximately 40-amino acid F-box motif. F-box proteins interact with SKP1 through the F box| and they interact with ubiquitination targets through other protein interaction domains.

Research_area:Cell biology; Epigenetics and nuclear signaling

Target_protein:FBXL18

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:FXL18

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):88550

UniProt accession:Human: Q96ME1

Synonyms:FXL18

GeneID:Human: 80028