FOXL2 Antibody - Cat. #: CSB-PA981648

SKU: CSB-PA981648

Size :50ul

Clone Number:

Aliases:Blepharophimosis antibody; Blepharophimosis epicanthus inversus and ptosis 1 antibody; Blepharophimosis epicanthus inversus and ptosis antibody; BPES 1 antibody; BPES antibody; BPES1 antibody; Epicanthus inversus and ptosis 1 antibody; Forkhead box L2 antibody; Forkhead box protein L2 antibody; Forkhead transcription factor FOXL2 antibody; FOX L2 antibody; FOXL 2 antibody; FOXL2 antibody; FOXL2_HUMAN antibody; PFRK antibody; PINTO antibody; PITUITARY FORKHEAD FACTOR antibody; POF 3 antibody; POF3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P58012

Immunogen:Synthetic peptide of Human FOXL2

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; ELISA:1:1000-1:5000, WB:1:500-1:2000

Background:This gene encodes a forkhead transcription factor. The protein contains a fork-head DNA-binding domain and may play a role in ovarian development and function. Mutations in this gene are a cause of blepharophimosis syndrome and premature ovarian failure 3. Critical factor essential for ovary differentiation and maintenance, and repression of the genetic program for somatic testis determination. Prevents trans-differentiation of ovary to testis through transcriptional repression of the Sertoli cell-promoting gene SOX9. Activates SIRT1 transcription under cellular stress conditions. Activates transcription of OSR2.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FOXL2

Research Areas:Epigenetics and Nuclear Signaling