FMR1 Antibody - Cat. #: CSB-PA916967

SKU: CSB-PA916967

Size :50ul

Clone Number:

Aliases:FMR 1 antibody; Fmr1 antibody; Fmr1 gene antibody; FMR1_HUMAN antibody; FMRP antibody; Fragile X mental retardation 1 antibody; Fragile X mental retardation 1 protein antibody; Fragile X mental retardation protein 1 antibody; Fragile X mental retardation protein antibody; fragile X mental retardation syndrome-related protein 1 antibody; fragile X mental retardation; autosomal homolog 1 antibody; FRAXA antibody; fxr1 antibody; MGC87458 antibody; POF antibody; POF1 antibody; Protein FMR-1 antibody; Protein FMR1 antibody; wu:fb16f11 antibody; wu:fd18c10 antibody; zgc:66226 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q06787

Immunogen:Fusion protein of Human FMR1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, IHC; ELISA:1:2000-1:5000, IHC:1:50-1:200

Background:The protein encoded by this gene binds RNA and is associated with polysomes. The encoded protein may be involved in mRNA trafficking from the nucleus to the cytoplasm. A trinucleotide repeat (CGG) in the 5' UTR is normally found at 6-53 copies, but an expansion to 55-230 repeats is the cause of fragile X syndrome. Expansion of the trinucleotide repeat may also cause one form of premature ovarian failure (POF1). Multiple alternatively spliced transcript variants that encode different protein isoforms and which are located in different cellular locations have been described for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FMR1

Research Areas:Epigenetics and Nuclear Signaling?Neuroscience