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GeneBio Systems

Fluor®Violet 500 Anti-Rat CD45 Antibody[OX-1]

Fluor®Violet 500 Anti-Rat CD45 Antibody[OX-1]

SKU:GBS-F1227UR

Regular price £320.00 GBP
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Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD45

Target Synonym: LCA; Ly-5; T200;Leukocyte common antigen;Ptprc;Receptor-type tyrosine-protein phosphatase C

Research Areas:

Conjugation:Elab Fluor®Violet 500

Host:Mouse

Species reactivity:Rat

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 µg/106 cells in 100 µL volume].

Isotype:Mouse IgG1, κ

Clonality:Monoclonal

Clone NO.:OX-1

UNIProt ID:P04157

Background:CD45 is a 180-220 kD protein also known as leukocyte common antigen (LCA). It is a protein tyrosine phosphatase with multiple isoforms differing as a result of alternative splicing of the extracellular domain and glycosylation. CD45 is expressed on all hematopoietic cells except erythrocytes and platelets; isoform expression depends on cell type, activation state, and cell maturation. CD45 functions in signal transduction through T and B cell antigen receptors. CD45 has been shown to interact with various proteins including galectin-1, CD2, CD3, and CD4. The OX-1 antibody has been shown to partially inhibit NK cell-mediated lysis of syngeneic tumor cells in vitro.

Concentration:

Control catalog number:E-AB-F09793R

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:19265

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