Fluor® Violet 450 Anti-Mouse CD49b/pan-NK cells Antibody[DX5]

SKU: GBS-F1116UQ

Size:100μg

Storage:This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD49b;pan-NK cells

Target Synonym:CD49 antigen-like family member B;CD49b;Collagen receptor;GPIa;Integrin alpha-2;Platelet membrane glycoprotein Ia;VLA-2 subunit alpha

Research Areas:Cell Adhesion;Cell Biology;Immunology;Innate Immunity

Conjugation:Elab Fluor®Violet 450

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10⁶ cells in 100 μL volume].

Isotype:Rat IgM, κ

Clonality:Monoclonal

Clone NO.:DX5

UNIProt ID:Q62469

Background:DX5 antigen has been recently characterized as CD49b. It is a 150 kD integrin α chain also known as α2 integrin, VLA-2 α chain, and integrin α2 chain. CD49b non-covalently associates with CD29 (β1 integrin) to form the CD49b/CD29 complex known as VLA-2, a receptor for collagen and laminin. CD49b is expressed on platelets, the majority of NK cells, NKT cells, and a small subset of CD8+ T cells (this population can be significantly increased following viral infection). DX5 is used for the identification and isolation of NK cells, and is especially useful for identifying NK cells in mice lacking the NK1.1 antigen.

Concentration:0.5 mg/mL

Control catalog number:E-AB-F09773Q

Immunogen:

Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.

Purification method:

Dilution:

GeneID:16398