FKBP1B Rabbit pAb

SKU: ES16392

Size: 100μL

Source:Rabbit

Applications:IHC; ELISA

Reactivity:Human;Rat;Mouse;

Dilution:IHC-p 1:50-200, ELISA(peptide)1:5000-20000

Immunogen:Synthesized peptide derived from human FKBP1B AA range: 35-85

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):

Human_gene_id:2281

Human_swiss_prot_no:P68106

Subcellular_location:Cytoplasm . Sarcoplasmic reticulum .

Other_name:Peptidyl-prolyl cis-trans isomerase FKBP1B (PPIase FKBP1B;EC 5.2.1.8;12.6 kDa FK506-binding protein;12.6 kDa FKBP;FKBP-12.6;FK506-binding protein 1B;FKBP-1B;Immunophilin FKBP12.6;Rotamase;h-FKBP-12)

Background:The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin. It is highly similar to the FK506-binding protein 1A. Its physiological role is thought to be in excitation-contraction coupling in cardiac muscle. There are two alternatively spliced transcript variants of this gene encoding different isoforms. [provided by RefSeq, Jul 2008],