FKBP12/FKBP1A Monoclonal Antibody

SKU: AN200098P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies

Abbreviation:FKBP1A

Target Synonym:PKC;PKCI;FKBP1A;FKBP-12;FKBP-1A;FKBP1;FKBP12;PKC12;PKCI2;PPIASE;12 kD;12 kDa FK506-binding protein;12 kDa FKBP;Calstabin 1;FK506 binding protein;FK506 binding protein 1;FK506 binding protein 12;FK506 binding protein 1A;FK506 binding protein 1A (12kD);FK506 binding protein 1A 12kDa;FK506 binding protein T cell 12 kD;FK506 binding protein12;FK506-binding protein 1A;FKB1A;FKBP 12;FKBP 1A;FKBP12 Exip3;FKBP12C;Immunophilin FKBP12;Peptidyl prolyl cis trans isomerase;Peptidyl-prolyl cis-trans isomerase FKBP1A;PPIase FKBP1A;Protein kinase C inhibitor 2;Rotamase;T cell

Research Areas:Immunology

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:WB

Isotype:IgG1

Clonality:Monoclonal

Clone NO.:4D1

UNIProt ID:P62942

Accession:

Background:The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. The protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK503 and rapamycin. It interacts with several intracellular signal transduction proteins including type I TGF-beta receptor. It also interacts with multiple intracellular calcium release channels, and coordinates multi-protein complex formation of the tetrameric skeletal muscle ryanodine receptor. In mouse, deletion of this homologous gene causes congenital heart disorder known as noncompaction of left ventricular myocardium. Multiple alternatively spliced variants, encoding the same protein, have been identified. The human genome contains five pseudogenes related to this gene, at least one of which is transcribed.

Concentration:1 mg/mL

Immunogen:Recombinant Human FKBP1A protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000;

Calculated MW:12 kDa

ObservedMW:15 kDa