FHL2 Antibody - Cat. #: CSB-PA131696

SKU: CSB-PA131696

Size :100ul

Clone Number:

Aliases:AAG 11 antibody; AAG11 antibody; Aging associated gene 11 antibody; Down regulated in rhabdomyosarcoma LIM protein antibody; Downregulated in rhabdomyosarcoma LIM protein antibody; DRAL antibody; FHL 2 antibody; FHL-2 antibody; Fhl2 antibody; FHL2 protein antibody; FHL2_HUMAN antibody; Four and a half LIM domain protein 2 antibody; Four and a half LIM domains 2 antibody; Four and a half LIM domains protein 2 antibody; KIAA0990 antibody; LIM domain protein DRAL antibody; Skeletal muscle LIM protein 3 antibody; Skeletal muscle LIM-protein 3 antibody; SLIM 3 antibody; SLIM-3 antibody; SLIM3 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14192

Immunogen:Peptide sequence around aa.16~28 (I-L-R-E-E) derived from Human FHL2.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

May function as a molecular transmitter linking various signaling pathways to transcriptional regulation. Negatively regulates the transcriptional repressor E4F1 and may function in cell growth. Inhibits the transcriptional activity of FOXO1 and its apoptotic function by enhancing the interaction of FOXO1 with SIRT1 and FOXO1 deacetylation.

Genini M., Schwalbe P., Scholl F.A., Remppis A., Mattei M.-G., Schaefer B.W.DNA Cell Biol. 16:433-442(1997)

Tanahashi H., Tabira T.Hum. Mol. Genet. 9:2281-2289(2000)

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Conjugate:Non-conjugated

Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FHL2

Research Areas:Epigenetics and Nuclear Signaling