FGR Monoclonal Antibody

SKU: BT-MCA3492

Size:100μL

Background:FGR: Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog, also known as SRC2; c-fgr; c-src2; FLJ43153; MGC75096; p55c-fgr; p58c-fgr. It is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Research_area:Signal Transduction

Target_protein:FGR

applications:WB, IHC

Reactivity:Human, Mouse

Clonality:Monoclonal

Clone ID:6G2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FGR

Immunogen:Purified recombinant fragment of human FGR expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):56kDa

UniProt accession:P09769

Synonyms:SRC2, c-fgr, c-src2, p55c-fgr, p58c-fgr

GeneID:2268