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Gene Bio Systems

FGFRL1 Antibody - Cat. #: CSB-PA028033

FGFRL1 Antibody - Cat. #: CSB-PA028033

SKU:CSB-PA028033

Regular price £292.00 GBP
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Size :50ul

Clone Number:

Aliases:FGF homologous factor receptor antibody; FGF receptor like protein 1 antibody; FGF receptor-like protein 1 antibody; FGFR 5 antibody; FGFR like protein antibody; FGFR-5 antibody; FGFR-like protein antibody; FGFR5 antibody; Fgfrl1 antibody; FGRL1_HUMAN antibody; FHFR antibody; Fibroblast growth factor receptor 5 antibody; Fibroblast growth factor receptor like 1 antibody; Fibroblast growth factor receptor-like 1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q8N441

Immunogen:Fusion protein of Human FGFRL1

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; ELISA:1:2000-1:10000, WB:1:200-1:1000, IHC:1:100-1:300

Background:The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FGFRL1

Research Areas:Signal transduction

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