FCN1 Antibody - Cat. #: CSB-PA008550ESR1HU

SKU: CSB-PA008550ESR1HU

Size :50ul

Clone Number:

Aliases:Collagen/fibrinogen domain containing protein 1 antibody; Collagen/fibrinogen domain-containing protein 1 antibody; Fcn1 antibody; FCN1_HUMAN antibody; FCNM antibody; ficolin (collagen/fibrinogen domain containing) 1 antibody; Ficolin 1 antibody; Ficolin A antibody; Ficolin alpha antibody; Ficolin-1 antibody; Ficolin-A antibody; Ficolin-alpha antibody; M ficolin antibody; M-ficolin antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:O00602

Immunogen:Recombinant Human Ficolin-1 protein (30-326AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Extracellular lectin functioning as a pattern-recognition receptor in innate immunity. Binds the sugar moieties of pathogen-associated molecular patterns (PAMPs) displayed on microbes and activates the lectin pathway of the complement system. May also activate monocytes through a G protein-coupled receptor, FFAR2, inducing the secretion of interleukin-8/IL-8 (PubMed:21037097). Binds preferentially to 9-O-acetylated 2-6-linked sialic acid derivatives and to various glycans containing sialic acid engaged in a 2-3 linkage.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FCN1

Research Areas:Immunology