FBP1 Antibody - Cat. #: CSB-PA008459ESR2HU

SKU: CSB-PA008459ESR2HU

Size :50ul

Clone Number:

Aliases:6-bisphosphatase 1 antibody; 6-bisphosphate 1-phosphohydrolase 1 antibody; D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody; D-fructose-1 antibody; EC 3.1.3.11 antibody; F16P1_HUMAN antibody; FBP antibody; FBP 1 antibody; FBP1 antibody; FBPase 1 antibody; Fructose 1 6 bisphosphatase 1 antibody; Fructose bisphosphatase 1 antibody; Fructose-1 antibody; Growth inhibiting protein 17 antibody; Liver fructose bisphosphatase antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P09467

Immunogen:Recombinant Human Fructose-1,6-bisphosphatase 1 protein (1-338AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, IHC; Recommended dilution: IHC:1:20-1:200

Background:Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FBP1

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Metabolism; Signal transduction