FBLN5 Monoclonal Antibody

SKU: BT-MCA2065

Size:100μL

Background:FBLN5: fibulin 5. The protein is a secreted, extracellular matrix protein containing an Arg-Gly-Asp (RGD) motif and calcium-binding EGF-like domains. It promotes adhesion of endothelial cells through interaction of integrins and the RGD motif. It is prominently expressed in developing arteries but less so in adult vessels. However, its expression is reinduced in balloon-injured vessels and atherosclerotic lesions, notably in intimal vascular smooth muscle cells and endothelial cells. Therefore, the protein encoded by this gene may play a role in vascular development and remodeling.

Research_area:Signal Transduction

Target_protein:FBLN5

applications:IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:1G6A4

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:FBLN5

Immunogen:Purified recombinant fragment of FBLN5 (aa242-448) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:Q9UBX5

Synonyms:EVEC, UP50, ARMD3, DANCE

GeneID:10516