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Gene Bio Systems

FASLG Antibody - Cat. #: CSB-PA243242

FASLG Antibody - Cat. #: CSB-PA243242

SKU:CSB-PA243242

Regular price £513.00 GBP
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Size :100ul

Clone Number:

Aliases:ALPS1B antibody; Apoptosis (APO 1) antigen ligand 1 antibody; Apoptosis antigen ligand 1 antibody; Apoptosis antigen ligand antibody; APT1LG1 antibody; APTL antibody; CD178 antibody; CD178 antigen antibody; CD95 ligand antibody; CD95-L antibody; CD95L antibody; CD95L protein antibody; Fas antigen ligand antibody; Fas L antibody; Fas ligand (TNF superfamily member 6) antibody; Fas ligand antibody; FASL antibody; Fasl Fas ligand (TNF superfamily member 6) antibody; FASLG antibody; Generalized lymphoproliferative disease antibody; Gld antibody; soluble form antibody; TNFL6_HUMAN antibody; TNFSF6 antibody; Tumor necrosis factor (ligand) superfamily member 6 antibody; Tumor necrosis factor ligand superfamily member 6 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P48023

Immunogen:Synthesized peptide derived from internal of Human FAS ligand.

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. The FasL intracellular domain (FasL ICD) cytoplasmic form induces gene transcription inhibition.

Alderson M.; J. Exp. Med. 181:71-77(1995).
Takahashi T., Int. Immunol. 6:1567-1574(1994).
Gregory S.G., ure 441:315-321(2006).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:FASLG

Research Areas:Cell biology;Immunology;Stem cells

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