FADD (Ab-191) Antibody - Cat. #: CSB-PA975869

SKU: CSB-PA975869

Size :100ul

Clone Number:

Aliases:Fadd antibody; Mort1FAS-associated death domain protein antibody; FAS-associating death domain-containing protein antibody; Mediator of receptor induced toxicity antibody; Protein FADD antibody

Product Type:Polyclonal Antibody

Immunogen Species:Mus musculus (Mouse)

UniProt ID:Q61160

Immunogen:Synthesized peptide derived from C-terminal of Human FADD.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Apoptotic adaptor molecule that recruits caspase-8 or caspase-10 to the activated Fas (CD95) or TNFR-1 receptors. The resulting aggregate called the death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation. Active caspase-8 initiates the subsequent cascade of caspases mediating apoptosis By similarity. Involved in interferon-mediated antiviral immune response, playing a role in the positive regulation of interferon signaling By similarity.

Zhang J., Mol. Cell. Biol. 16:2756-2763(1996).
Hsu H., Cell 84:299-308(1996).
Carninci P., Science 309:1559-1563(2005)

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:Fadd/FADD

Research Areas:Cancer;Cell biology