ETBR Polyclonal Antibody

SKU: BT-AP03095

Size:100μL

Background:The protein encoded by EDNRB (endothelin receptor type B) is a G protein-coupled receptor which activates a phosphatidylinositol-calcium second messenger system. Its ligand, endothelin, consists of a family of three potent vasoactive peptides: eT1, ET2, and ET3. Studies suggest that the multigenic disorder, Hirschsprung disease type 2, is due to mutations in the endothelin receptor type B gene. Alternatively spliced transcript variants encoding different isoforms have been found for EDNRB.

Research_area:Signal Transduction

Target_protein:ETBR

applications:WB, IHC-p, ELISA

Reactivity:Human

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:ETBR Antibody

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):49644

UniProt accession:Human: P24530; Mouse: P48302

Synonyms:Endothelin B receptor (ET-B) (ET-BR) (Endothelin receptor non-selective type)

GeneID:Human: 1910; Mouse: 13618