EST3 Rabbit Polyclonal Antibody

SKU: BT-AP09789

Size:100μL

Background:This gene encodes a member of the carboxylesterase large family. The family members are responsible for the hydrolysis or transesterification of various xenobiotics| such as cocaine and heroin| and endogenous substrates with ester| thioester| or amide bonds. They may participate in fatty acyl and cholesterol ester metabolism| and may play a role in the blood-brain barrier system. This gene is expressed in several tissues| particularly in colon| trachea and in brain| and the protein participates in colon and neural drug metabolism. Multiple alternatively spliced transcript variants encoding distinct isoforms have been reported| but the biological validity and/or full-length nature of some variants have not been determined.

Research_area:Metabolism; Signal transduction

Target_protein:CES3

applications:WB

Reactivity:Human, Rat, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:EST3

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):

UniProt accession:Human: Q6UWW8

Synonyms:EST3; Carboxylesterase 3; EC 3.1.1.1; Liver carboxylesterase 31 homolog)

GeneID:Human: 23491