ENY2 Antibody, Biotin conjugated - Cat. #: CSB-PA889067LD01HU

SKU: CSB-PA889067LD01HU

Size :50ug

Clone Number:

Aliases:1810057B09Rik antibody; 6720481I12 antibody; DC6 antibody; e(y)2 antibody; Enhancer of yellow 2 transcription factor homolog antibody; eny2 antibody; ENY2_HUMAN antibody; Ey2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9NPA8

Immunogen:Recombinant Human Transcription and mRNA export factor ENY2 protein (1-101AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Involved in mRNA export coupled transcription activation by association with both the TREX-2 and the SAGA complexes. The transcription regulatory histone acetylation (HAT) complex SAGA is a multiprotein complex that activates transcription by remodeling chromatin and mediating histone acetylation and deubiquitination. Within the SAGA complex, participates in a subcomplex that specifically deubiquitinates both histones H2A and H2B. The SAGA complex is recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation. The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ENY2

Research Areas:Epigenetics and Nuclear Signaling; Cell biology; Signal transduction