Endostatin antibody , Cat. # FNab02762

SKU: FNab02762

Size:100ug

Purification:Immunogen affinity purified

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Rabbit

Clonality:polyclonal

Clone ID:

Isotype:IgG

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Endostatin is a naturally-occurring 20-kDa C-terminal fragment derived from COL18A1(also named as KNO). It is reported to serve as an anti-angiogenic agent, similar to angiostatin and thrombospondin. It potently inhibits endothelial cell proliferation and inhibits endothelial cell angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling. Endostatin is a broad spectrum angiogenesis inhibitor and may interfere with the pro-angiogenic action of growth factors such as basic fibroblast growth factor(bFGF/FGF-2) and vascular endothelial growth factor(VEGF).

Immunogen:collagen, type XVIII, alpha 1

Synonyms:Endostatin

Observed MW:19 kDa, 27 kDa

Uniprot ID:P39060

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:200-1:1000; IHC: 1:20-1:200

Gene ID:

Research Area:Cardiovascular, Developmental biology