ELP2 Polyclonal Antibody

SKU: E-AB-10941

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:ELP2

Target Synonym:AU023723;Elongation protein 2 homolog (S. cerevisiae);Elongator acetyltransferase complex subunit 2;Elongator complex protein 2;elongator protein 2;ELP2;ELP2;Epl2;FLJ10879;SHINC 2;SHINC-2;SHINC2;signal transducer and activator of transcription 3 interacting protein 1;signal transducer and activator of transcription interacting protein 1;STAT3 interacting protein 1;Stat3 interacting protein;STAT3-interacting protein 1;STATIP 1;STATIP1;STATIP1 protein;StIP;StIP1

Research Areas:Epigenetics and Nuclear Signaling;Signal Transduction

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat

Application:IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:Q6IA86

Accession:

Background:One member of the STAT family, Stat3, participates in a wide range of biological processes including nephrogenesis, gliogenesis, hepatogenesis, T cell proliferation, inflammation and oncogenesis. Many of these responses are triggered by the IL-6 family of cytokines, which transduce their vital signals through a common gp130 receptor chain . A novel Stat3-Interacting Protein, StIP1, contains 12 WD40 repeats, which mediate protein-protein interactions . StIP1 exhibits an affinity for members of the JNK family and may play a specific role in regulating Stat3 activation. Overexpression of StIP1 blocks Stat3 activation, nuclear translocation and Stat3-dependent induction of a reporter gene, suggesting that StIP1 regulates the ligand-dependent activation of Stat3, probably by serving as a scaffold protein that promotes the interaction between JNK and the Stat3 substrate.

Concentration:0.4 mg/mL

Immunogen:Recombinant protein of human ELP2

Buffer:PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification method:Affinity purification

Dilution:IHC 1:50-1:200

Calculated MW:

ObservedMW: