ELL Antibody - Cat. #: CSB-PA795035

SKU: CSB-PA795035

Size :100ul

Clone Number:

Aliases:ELL antibody; C19orf17RNA polymerase II elongation factor ELL antibody; Eleven-nineteen lysine-rich leukemia protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P55199

Immunogen:Synthesized peptide derived from internal of Human ELL.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:3000

Background:Elongation factor component of the super elongation complex (SEC), a complex required to increase the catalytic rate of RNA polymerase II transcription by suppressing transient pausing by the polymerase at multiple sites along the DNA. ELL also plays an early role before its assembly into in the SEC complex by stabilizing RNA polymerase II recruitment/initiation and entry into the pause site. Required to stabilize the pre-initiation complex and early elongation.

Thirman M.J., Proc. Natl. Acad. Sci. U.S.A. 91:12110-12114(1994).
Simone F., Blood 98:201-209(2001).
Kong S.E., Proc. Natl. Acad. Sci. U.S.A. 102:10094-10098(2005).

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:ELL

Research Areas:Epigenetics and Nuclear Signaling;Cancer