ELF3 Polyclonal Antibody

SKU: E-AB-19002

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: ELF3

Target Synonym: E74 like factor 3;E74 like factor 3 ets domain transcription factor;E74 like factor 3 ets domain transcription factor epithelial specific;E74 like factor 3 ETS domain transcription factor serine box epithelial specific;E74-like factor 3;Elf3;ELF3;Epithelial restricted with serine box ;Epithelial-restricted with serine box;Epithelium restricted Ets protein ESX;Epithelium specific Ets factor 1;Epithelium specific Ets transcription factor 1;Epithelium-restricted Ets protein ESX;Epithelium-specific Ets transcription factor 1;EPR 1;EPR1;ERT;ESE-1;ESX;Ets domain transcription factor serine box;Ets domain transcription factor serine box epithelial specific;Ets transcription factor;ETS-related transcription factor Elf-3;jen;MGC139318

Research Areas: Cancer;Epigenetics and Nuclear Signaling

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human

Application: IHC

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P78545

Accession:

Background: Transcriptional activator that binds and transactivates ETS sequences containing the consensus nucleotide core sequence GGA[AT]. Acts synergistically with POU2F3 to transactivate the SPRR2A promoter and with RUNX1 to transactivate the ANGPT1 promoter. Also transactivates collagenase, CCL20, CLND7, FLG, KRT8, NOS2, PTGS2, SPRR2B, TGFBR2 and TGM3 promoters. Represses KRT4 promoter activity. Involved in mediating vascular inflammation. May play an important role in epithelial cell differentiation and tumorigenesis. May be a critical downstream effector of the ERBB2 signaling pathway. May be associated with mammary gland development and involution. Plays an important role in the regulation of transcription with TATA-less promoters in preimplantation embryos, which is essential in preimplantation development (By similarity).

Concentration: 1.68 mg/mL

Immunogen: Fusion protein of human ELF3

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: IHC 1:50-1:300

Calculated MW:

ObservedMW: