eIF4B(Phospho Ser422) Polyclonal Antibody

SKU: BT-AP15387

Size:100μL

Background:Required for the binding of mRNA to ribosomes. Functions in close association with EIF4-F and EIF4-A. Binds near the 5'-terminal cap of mRNA in presence of EIF-4F and ATP. Promotes the ATPase activity and the ATP-dependent RNA unwinding activity of both EIF4-A and EIF4-F.,Contains 1 RRM (RNA recognition motif) domain.,subunit:Self-associates and interacts with EIF3 p170 subunit.,

Research_area:Epigenetics and nuclear signaling

Target_protein:EIF4B

applications:WB, IHC-p, IF, ICC, ELISA

Reactivity:Human, Mouse

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:Eukaryotic translation initiation factor 4B

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):69224

UniProt accession:Human: P23588; Mouse: Q8BGD9

Synonyms:Eukaryotic translation initiation factor 4B; EIF4B; Eukaryotic translation initiation factor 4B; eIF-4B

GeneID:Human: 3716; Mouse: 75705